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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCC All Species: 45.45
Human Site: S330 Identified Species: 76.92
UniProt: Q15814 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q15814 NP_003183.1 346 39220 S330 W L A R D M A S P N W S I L P
Chimpanzee Pan troglodytes XP_518477 346 39236 S330 W L A R D M A S P N W S I L P
Rhesus Macaque Macaca mulatta XP_001088723 346 39322 S330 W L A R D M A S P N W S I L P
Dog Lupus familis XP_538923 388 42549 S372 W L A R D T A S P N W S I L P
Cat Felis silvestris
Mouse Mus musculus Q8VCN9 341 38106 S325 W L A R N V A S P N W S I L P
Rat Rattus norvegicus NP_001101670 340 38058 S324 W L A Q N V P S P N W S I L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508991 335 37102 S319 W L V Q G V A S P N W S V L P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922489 350 39443 S325 W L A A G T P S P N W T V I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722959 355 40503 S315 W L S P D V P S P N W S L L K
Honey Bee Apis mellifera XP_001120828 342 39209 S326 W L S N E K H S P N W S I L D
Nematode Worm Caenorhab. elegans Q27249 256 29613 E245 R V R N L T E E I E Q T V Q E
Sea Urchin Strong. purpuratus XP_783718 353 39965 S337 W L A H D K H S P N W G L L P
Poplar Tree Populus trichocarpa XP_002307082 324 36492 S307 K W L R A V K S P N W S V L E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_195702 345 38291 S324 R W L R A V Q S P N W S L L P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.3 72.9 N.A. 76 74.5 N.A. 61.5 N.A. N.A. 43.7 N.A. 33.5 38.7 21.1 39.6
Protein Similarity: 100 99.1 97.6 78.3 N.A. 84.3 83.5 N.A. 74.5 N.A. N.A. 64 N.A. 57.7 58 40.1 62.6
P-Site Identity: 100 100 100 93.3 N.A. 86.6 73.3 N.A. 66.6 N.A. N.A. 53.3 N.A. 60 60 0 66.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 93.3 N.A. 86.6 N.A. N.A. 73.3 N.A. 80 73.3 20 73.3
Percent
Protein Identity: 29.7 N.A. N.A. 32.3 N.A. N.A.
Protein Similarity: 48.2 N.A. N.A. 51.7 N.A. N.A.
P-Site Identity: 46.6 N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 60 N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 58 8 15 0 43 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 43 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 8 8 0 8 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 15 0 0 0 0 0 0 8 0 0 0 % G
% His: 0 0 0 8 0 0 15 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 50 8 0 % I
% Lys: 8 0 0 0 0 15 8 0 0 0 0 0 0 0 8 % K
% Leu: 0 79 15 0 8 0 0 0 0 0 0 0 22 86 0 % L
% Met: 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 15 0 0 0 0 93 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 22 0 93 0 0 0 0 0 72 % P
% Gln: 0 0 0 15 0 0 8 0 0 0 8 0 0 8 0 % Q
% Arg: 15 0 8 50 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 15 0 0 0 0 93 0 0 0 79 0 0 0 % S
% Thr: 0 0 0 0 0 22 0 0 0 0 0 15 0 0 0 % T
% Val: 0 8 8 0 0 43 0 0 0 0 0 0 29 0 0 % V
% Trp: 79 15 0 0 0 0 0 0 0 0 93 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _